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Supplementary file 2 depicts that encompassed studies presented with low reporting bias with a median score of 8 out of a probable score of 10 (overall agreement 85.67%, kappa = 0.71), good external legitimacy with median score of 2 out of 3 (overall agreement 39.13%, kappa = 0.13), excellent internal validity with median score 7 out of 7 (overall agreement 65.22%, kappa = 0.34) and low risk assortment bias with median of 5 out of possible 6 (overall agreement 56.51%, kappa = 0.19)

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