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It is the dimeric C3b within these complexes that renders them efficient activators of the alternative complement pathway
The beneficial effects of mangiferin are primarily due to its antioxidant properties, as evidenced by increased levels of GPx, GST, CAT, and SOD, and its anti-inflammatory effects, indicated by decreased levels of NF-B, TNF-, IL-1, IL-6, and IL-10 [ 67 ]
Dodge ML, Wander RC, Xia Y, Butler JA, Whanger PD
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N Engl J Med 319:223226
