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Nrf2 and HIF1 converge to arsenic-induced metabolic reprogramming and the formation of the cancer stem-like cells
Nrf2 signaling, an important regulator of antioxidant defense, is impaired during aging [60], leading to reduced levels of antioxidant enzymes like CAT or SOD [62]
Although cleaved CASPASE-3 is the definitive marker of irreversible apoptosis, this study relied on ELISA and qRT-PCR methods to evaluate CASPASE-3expression
The copper component is crucial
