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Restoration of DLEC1 expression resulted in reduced anchorage-independent growth of HT29 cells, indicating suppressed tumorigenic potential (17)
The toxicity of 5-azadC limits its clinical application, but combining it with histone deacetylase inhibitors like sodium butyrate has shown synergistic effects in FXS lymphoblastoid cell lines, leading to more effective restoration of FMR1 gene activity
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ORCID iDs: Jos Luis Izquierdo Julio Ancochea References 1.Zhu N, Zhang D, Wang Wet al
