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The importance of the resistance was not recognized until outbreaks of malaria began in 1969 and neither DDT nor HCH was effective
As these were already lower in the mutants compared to the WT this led to stronger phenotypes regarding root length and total biomass production
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in vivo inhibition of l-buthionine-(S,R)-sulfoximine-induced cataracts by a novel antioxidant, N-acetylcysteine amide
