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Dysregulated lipid metabolism links NAFLD to cardiovascular disease

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Therefore, while HRAS mutations are typical of Spitz nevi, demonstrating their presence is no guarantee of a benign lesion, since they can also be found in Spitz melanoma.48,49 However, given that HRAS mutations are found in less than 1% of melanomas,37 their presence in a Spitz tumor is reassuring

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