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Vitamins in the prevention of human diseases
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gshT mutant included virulence-determinant genes such as speB , encoding the cysteine protease streptococcal pyrogenic exotoxin B and adjacent cotranscribed genes ( spi , a SpeB inhibitor
Studies suggest that various molecular pathways are involved in IC/BPS, including the JUN N-terminal kinase (JNK) pathway, transient receptor potential (TRP) channels, activated mast cells, mucosal signalling, circadian rhythm regulation, inflammation and neural dysregulation
