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Impact of an AGEpromoting diet on sperm integrity and the protective effects of antioxidant/antiAGE treatments To better understand how an AGEpromoting diet and various corrective treatments affect sperm integrity, we performed a detailed evaluation of sperm nuclear parameters (histone retention, protamine deficiency, DNA fragmentation), lipid peroxidation, and intracellular ROS

The temperature should not exceed 40 degrees and the pH should be between 3-6

Stabilized -catenin translocates to nuclei and binds to T-cell factor/lymphoid enhancer-binding factor (TCF-LEF) to induce expression of the MITF gene [35,36]

DNA damage from chemotherapy can contribute to drug resistance in cancer cells (Goldstein and Kastan, 2015), cause collateral damage to healthy tissues (Liu et al., 2021), and increase the risk of secondary malignancies due to mutagenic effects (Marcus et al., 2021)