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361, 12681278.10.1056/NEJMoa0809335 191 OzsoyO.Seval-CelikY.HaciogluG.YargicogluP.DemirR.AgarA.AslanM

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However, before the onset of clinically diagnosable motor symptoms, most patients experience several non-motor symptoms, including depression, apathy, dementia, rapid eye movement (REM), sleep behavior disorder (RBD), and GI-associated disorders, including reduced gastric emptying and constipation (Seppi et al., 2011

Deprenyl, a selective MAO-B inhibitor, up-regulates NRF2 and NQO1 to protect PC12 and SH-SY5Y cells against MPP + -induced toxicity [278,279]