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A cell-free high-throughput screening system and subsequent bioassays found two tetrafluorophthalimide-based compounds, Everlastin1 and Everlastin2, that inhibited the EPH1DNA interaction and delayed petal senescence

P.AtwoodC

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Additionally, the mutant huntingtin protein can impair the function of the transcription factor PGC-1, which is crucial for the regulation of antioxidant defenses and mitochondrial biogenesis