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This is especially important for those who may have difficulty absorbing nutrients due to digestive issues, certain medical conditions, or simply because of age-related changes

(2014) Serum Nutritional Biomarkers and Their Associations with Sleep among US Adults in Recent National Surveys

What we know about extended use The longest controlled human trials ran for 12 weeks

Deficiency can lead to megaloblastic anemia and neurologic complications, while elevated levels may signal underlying liver disease or malignancy