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Bersuker K, Hendricks JM, Li Z, et al

The most frequent side-effects are gastrointestinal discomfort including nausea, abdominal pain, vomiting, and diarrhea, which range from mild to moderate (Borgna-Pignatti and Marsella, Antioxidants Vitamin E Vitamin E is the most potent biological lipophilic chain-breaking antioxidant (Stocker, 2007), actually comprising -, -, -, and -tocopherols and -, -, -, and -tocotrienols

Usually, the amount of ALP-enzymatic product to accelerate the colorimetric reaction is related to the amount of ALP labels and targets

Document dosing rationales (route, concentration, frequency) and use pilot results to set dose escalation or fixeddose arms in the main study