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When thyroid activity is low, a condition called hypo thyroidism develops

The linear mixed model uses all individual measurements and accounts for repeated measures, while the model assessing differences in TMAO log AUC summarizes each participants response for direct comparisons between age-sex subgroups

In developed countries, excessive calorie intake and frequent consumption of unhealthy foods, associated with a sedentary lifestyle, have caused an increase in the prevalence of obesity, which in turn predisposes to several non-communicable diseases, such as cardiovascular disease, diabetes, hypertension, and chronic kidney disease [9]

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