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Moreover, the characterization of the lysosomal pathway undertaken by the 1 -ARs or 3 -ARs is less extensive and straightforward than that of the 2 -ARs (Bristow et al., 1982
& Wu, Y.-H
Our study demonstrated that these Ru(II) complexes are promising chemotherapeutic agents with oxidative stress induction and energy generation disturbance
From a therapeutic standpoint, their main opportunity may be combination design: pairing ferroptosis induction with interventions that remodel mitochondrial electron flow or substrate availability, thereby constraining the capacity to regenerate CoQ 10 H 2
