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Gut-microbiota-derived components and metabolism (e.g., LPS and palmitate) can induce the capillarization of LSECs to promote NASH, liver fibrosis, and HCC development via the products such as mitogenic factor sphingosine-1-phosphate (S1P) and vascular cell adhesion molecule-1 (VCAM-1) [103, 104]

Furthermore, respiratory serine proteases that belong to the TTSP family, increase host susceptibility to SARS-CoV infection-2 55

Among the clinical trials that failed to demonstrate cognitive benefits from B vitamin supplementation, one by Eussen et al

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