linus pauling institute glutathione peroxidase Frontiers Immunity In Brief | Linus

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doi: 10.1371/journal.pone.0016090 8 TarabanVYSlebiodaTJWilloughbyJEBuchanSLJamesSShethBet al

However, upon exposure to powerful pro-oxidant stimuli such as dapsone or primaquine, acute extravascular and then intravascular hemolysis can occur leading to the release of heme and free iron into the local intravascular environment 57

Instead, research points to the interaction of low MAO-A and childhood neglect or mistreatment in males, increasing the relative risk of aggression.[ref] Really rare mutations that significantly decrease MAOA levels in humans cause a genetic disease called Brunner syndrome, and the symptoms include impulsive and antisocial behavior.[ref] So the effect of low MAOA on impulsivity is real, but it isnt necessarily caused by the common variants that decrease MAOA in all individuals