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While investigation of FTS practices has grown rapidly since 2016 [15], evidence derives primarily from single-instrument feasibility and acceptability studies using qualitative or quantitative designs and small sample sizes (n = 1193) of people who use drugs (PWUD) [10,11,12,13, 16,17,18,19,20,21,22,23], which limit generalizability

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In this review, we describe recent discoveries providing evidence for the contribution of the GHGHRIGF1 axis on mitochondrial biogenesis, mitophagy (or autophagy), and mitochondrial function under multiple physiological conditions

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