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Description
Because the milligram amount is fixed, a lighter body gets more drug exposure per pound: roughly 22% more at 70 kg and about a third less at 120 kg, compared with a 90 kg reference. The dose still comes from response and tolerability, but a lighter person is running a hotter exposure at the same number on the vial
However, individuals with rare genetic conditions like Lebers hereditary optic neuropathy or those with known severe hypersensitivities to cobalt should avoid these shots

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