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Focusing on findings in rodents, Ron and Barak review the intracellular signalling cascades that underlie this transition and the molecular mechanisms that act against it.

These results provide further evidence for a role of mitochondrial carnitine acetyltransferase in facilitating transfer of acetyl groups across mitochondrial membranes, thus regulating the availability in the cytoplasm of acetyl-CoA, a substrate of choline acetyltransferase

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