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demonstrated that short-term mitochondrial permeability transition pore opening (aka mitoflash) induced a nuclear reprogramming by histone methylation, suggesting a novel mitochondrial regulation of nuclear epigenetics

doi: 10.1111/j.2047-2927.2014.00200.x 21 FlanniganRSchlegelPN

These experiments were significantly complicated by the fact that most biological assays are carried out in the presence of serum that contain lipoproteins

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