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This complex phytochemical matrix contributes to their high total phenolic content and underlies their strong antioxidant capacity and characteristic red-purple pigmentation, as well as their documented bioactivities related to cardiometabolic and inflammatory processes associated with the prevention of non-communicable diseases (NCDs) (105, 106)

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Research on the pore structure of GSDMD-NT has shown that it facilitates the passage of neutral and positively charged proteins while reducing the transport of negatively charged proteins, thereby promoting the passage of mature IL-1 and IL-18, and increasing the cytoplasmic persistence of acidic, negatively charged pro-IL-1 and pro-IL-18