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Sigalos, J.T., et al

The Lancet Neurology In the LEGATO-HD Phase 2 double-blind, placebo-controlled trial of laquinimod in patients with HD, laquinimod did not show a significant effect on motor symptoms assessed by the UHDRS-TMS but significantly reduced caudate volume loss compared with placebo at week 52

[Abstract]2025 Oct 7;122(40):e2502841122

This broad gene regulatory activity establishes a cellular environment primed for regeneration, with research demonstrating that GHK-Cu treatment resets aged gene expression patterns to match younger, healthier profiles
