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2 The disease includes chronic bronchitis and emphysema, and both are characterized by an inflamed airway that decreases the amount of oxygen that flows to your body tissues

These alterations drive transcriptional reprogramming, impair mitochondrial quality control, and amplify neuroimmune signaling

Handl J, Capek J, Majtnerova P et al (2019) Transient increase in cellular dehydrogenase activity after cadmium treatment precedes enhanced production of reactive oxygen species in human proximal tubular kidney cells

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