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Ddit3 , Bgn , Tmem150a , Sqstm1 , Hist1h2bc , Ccnd2 , Mxd4 , Ypel3 , Kdm5b , Mxra8 , and Grina , which were previously identified and preliminarily validated by single-cell sequencing, all exhibit increased expression with the replicative senescence of MEF cells and can serve as potential aging biomarkers for further investigation

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S-acetyl glutathione has been shown to cross the membrane of the mitochondria, increasing the organelle's activity and minimizing ROS.(5)

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