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Zhao, L., Tang, J., & Kim, S

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Many of the signaling cascades involved in embryonic hair development are redeployed during adult hair development, and hyperactivation or inappropriate maintenance of these signaling pathways can result in skin disorders and cancers

In addition, it has been demonstrated that CXCL12 modulates CX3CL1 homeostasis by regulating CX3CL1 expression as well as CX3CL1 cleavage rate under physiological conditions (Cook et al., in vivo , in the recovery phase of mice subjected to PT, in which pharmacological antagonism with AMD3100 resulted in reduced CX3CL1 levels, both membrane-bound and soluble (Walter et al., 2015)