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Description
The mechanism centres on hepatic lipid clearance: methionine, inositol, and choline work together to prevent fat accumulation in liver cells by accelerating the conversion of stored triglycerides into bile acids and very-low-density lipoproteins (VLDL) for transport out of the liver and into circulation

Notably, inhibition of the depalmitoylation enzyme acylprotein thioesterase 2 led to delayed onset and lower rates of melanoma in mice expressing melanocytespecific zinc finger DHHCtype palmitoyltransferase 13 and an MC1R variant

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