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Obesity: Excess body weight, particularly around the midsection, is a high-risk factor

Moreover, MSU relies on ITGB1 on the surface of macrophages to activate the inflammatory signaling pathway, which suggests that targeting and inhibiting integrins on the surface of macrophages to inhibit inflammation in MSU-induced inflammatory complications is one of the research directions for precision therapy

WHO's Global Tuberculosis Report 2022

A well-organized repair is stronger than one that's just "more." 4
