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Glutathione-related enzymes are involved in drug handling, and genetic differences in these systems have been studied in relation to cyclophosphamide toxicity risk in dogs

Uses: Acute iron toxicity (common in children after accidental ingestion)

In addition, we identified letrozole as an undeclared API in three samples that were declared to contain anastrozole

Leveraging its exceptionally low limit of quantitation (0.58 g/mL), APAP-SG is ideal for high-throughput U(H)PLC-MS/MS workflows designed to simultaneously track parent drug clearance and trace-level toxic pathway activation in minimal plasma volumes [2]