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598 Tissue-resident T cells exhibit metabolic profiles similar to those of proinflammatory macrophages, which utilize nuclear PKM2/STAT3 signaling to maintain persistent IL-1 and IL-6 production

In these studies, geroprotection was assessed based on extended lifespan, in comparison to E

The resulting NO accumulation exacerbates glutamate-induced neurotoxicity, contributing to neuronal ferroptosis (53)
