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doi: 10.4012/dmj.26.451
A less than optimal production of red blood cells may lead to a lowered oxygen carrying capacity of the blood, resulting in insufficient muscle perfusion
During ischemia, oxygen deprivation forces cells to rely on anaerobic metabolism, resulting in ATP depletion and impaired function of ion pumps such as Na/K-ATPase, leading to ionic imbalances [7]
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