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We performed non-targeted, accurate semiquantitative metabolomic analysis of human whole blood, plasma, and red blood cells during 3458 hr fasting of four volunteers

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Despite having several advantages like high transduction efficiency and the potential for long term transgene expression, viral vectors have certain disadvantages like increased immunogenicity (LV), prevailing cytotoxicity (LV), a small packing size (AAV), expensive large scale production (all vectors), and the risk of integrating viral sequences into the target genome (LV) 8

The composition of the lung microbiome is specific in patients with different species of bronchitis, which complicates the relationship between the two
