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When treating PD patients with thalamus substrate nucleus deep brain stimulation (STN-DBS), UA-associated functional brain connectivity can be employed to evaluate the therapeutic outcome (Chang et al., 2023)
However, glutathionylation was only been detected on Cys-531 and Cys-704 indicating a high degree of specificity for this redox modification that inactivates Complex I
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A study by Abdelaziz et al
