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Malformation of the mesencephalic aqueduct may be a significant pathogenetic factor

BrdU cell-proliferation assay The rate of DNA synthesis was determined from the incorporation of BrdU into cells (BrdU Cell Proliferation ELISA kit

Therefore, when tissues that express ketohexokinase encounter fructose, they rapidly phosphorylate fructose to fructose 1-phosphate and deplete intracellular ATP
