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Growth hormones anabolic effects in muscle are mediated in part via IGF-I (Kim, Barton, Muja et al., 2005), although IGF-I-independent pathways have also been proposed (Daughaday, 1989, Isaksson, Lindahl, Nilsson et al., 1988, Le Roith, Bondy, Yakar et al., 2001, Sotiropoulos, Ohanna, Kedzia et al., 2006)
Safety, side effects, and considerations Early animal studies show BPC 157 safety data as encouraging
Conversely, SNPs affecting GPX7 and neuroblastoma RAS viral ( v-ras ) oncogene homolog ( NRAS ) had a negative influence on OS in these individuals
doi: 10.1007/s00394-005-0558-7
