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However, a recent Cochrane review of randomized controlled trials found that citicoline had no benefit to acute ischemic stroke patients compared to placebo with respect to all-cause mortality (8 trials)

This neuroinflammatory state, along with disrupted neurotransmitter signaling, explains the acute and long-term neurological and cognitive symptoms observed in COVID-19 patients and long COVID cases

Acta Paediatr 1995;84:93-5
