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Targeting mitochondrial oxidative stress effectively lowers 4-HNE levels and preserves cardiac performance (Xiong et al., 2024)

Curcumin has shown synergistic effects with these drugs, such as enhancing T-cell-mediated anti-tumor immune responses by reducing programmed death-ligand 1 (PD-L1) expression levels (Han et al., 2025)

(A) Resting oxygen uptake (VO 2 ) and maximal oxygen uptake assessed during a maximal performance test

HuntKAZhernakovaATurnerGHeapGARFrankeLBruinenbergMet al