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Unguided self-medication carries many potential risks such as incorrect self-diagnosis, dangerous drug interactions, incorrect manner of administration, severe adverse reactions, and masking of severe disease

however, the effectiveness of selenium, which is predominantly a constituent of enzymes, is not proportional to the dose

Li S, Bian F, Yue L, Jin H, Hong Z, Shu G

Moreover, in certain physiological contexts, disulfide bonds serve as redox-sensitive molecular switches, thereby modulating peptide activity in response to changes in cellular oxidative stress or redox signaling ( Despite their structural and functional advantages, disulfide-containing peptides face notable limitations that restrict their broader therapeutic applications ( in vivo circulation, can generate heterogeneous mixtures of isomers with variable or undesired biological activity