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Fumarate-induced senescence in renal cysts of Fh1 / mice / Previous work demonstrated that the loss of FH in murine kidneys does not result in overt renal carcinomas, as observed in HLRCC patients, but rather in benign cysts 19
A number of recent investigations of the control of cell fate by mitophagy have enhanced our understanding of the mechanisms by which mitophagy regulates ototoxicity and other hearing-related diseases, providing opportunities for targeting mitochondria to treat ototoxicity
However, it does contain natural sugar derived from the lemon juice powder
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