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CBD has diverse effects on immune cells, including reducing inflammation by decreasing NO and cytokine levels in monocytes and macrophages, promoting degranulation in mast cells, inducing apoptosis in dendritic cells and lymphocytes, and modulating cytokine production in dendritic cells

Disulfiram/copper induces immunogenic cell death and enhances CD47 blockade in hepatocellular carcinoma

Moreover, cytosolic SULTs are presumed to play a crucial role in the detoxification processes occurring in the developing human fetus since no UGTs transcripts have been detected in fetal liver at 20 weeks of gestation (Strassburg et al., 2002)

All histological sections were blindly evaluated by the same investigator