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doi:10.1093/jac/12.5.489 Chang JY, Balch C, Puccio J, Oh HS

The brain-derived neurotrophic factor (BDNF) and its receptor, tyrosine kinase receptor B (TrkB), are essential and common mechanisms for the antidepressant effects of both the parent molecules of ketamines [i.e., S, R()ketamine, S(+)ketamine, and R()ketamine] and their active metabolites [i.e., (2R,6R)-hydroxynorketamine and of S(+)norketamine] (Yang et al., 2019)

Rev Paul Pediatr

Lenzi A, Lombardo F, Gandini L, Dondero F
