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Metabolomics from stimulated WT and Nos2 / macrophages suggest that BCKDH, OGDH and GCS are indeed targeted in a NO-dependent manner (Fig

Future research should focus on developing new compounds with enhanced selectivity and clearly demonstrated disease-modifying effects, as well as exploring their potential for intervention in the prodromal phase of PD

FIGURE 7 4 CHAC enzymes beyond mammals Research on ChaC-like proteins has primarily focused on the mammalian homologs CHAC1 and CHAC2, with very few studies characterizing these enzymes in other organisms

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