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Description
Sorting of proteins to the lysosomal pathway involves a maturation of endosomes from early to late endosomes through the multivesicular endosomes (MVEs)

De grootte van de liposomen is veel kleiner dan 500 nm, wat de grens is voor de ideale stabiliteit en biologische beschikbaarheid in het spijsverteringskanaal

Being mindful of these pitfalls is essential for success

In the CNS, melatonin is metabolized mainly by the enzyme indoleamine 2,3-dioxygenase (IDO), giving rise to the metabolite N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK), which is subsequently transformed into N-acetyl-5-methoxykynuramine (AMK) [1,6]
