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This DMF concentration didnt reduce cell viability under non-BSO pretreatment condition and reduced cell viability less than 5% under BSO pretreatment condition (Supplementary Figure S2)

That said, mild effects can occur in some people, especially when starting any new supplement: Temporary bloating or fullness (more common with collagen) Mild digestive discomfort if taken without enough water These are usually short-lived and can be reduced by: Taking supplements with adequate water Starting with recommended doses Choosing high-quality, well-absorbed formulations Using clinically formulated products from trusted brands helps minimize unnecessary reactions

Andrographolide, an anti-inflammatory multitarget drug: all roads lead to cellular metabolism

This neuroinflammatory cascade also heavily impacts the autonomic nervous system, contributing to the development of dysautonomia and Postural Orthostatic Tachycardia Syndrome (POTS)