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NRF2 may mitigate iron-death in Acute Lung Injury(ALI) by upregulating the production of antioxidant enzymes and associated genes, protecting alveolar epithelial cells, and minimizing lung damage [62]
Metabolic changes in host cell following biofilm infections are of growing importance for understanding the pathogenesis of bacterial biofilm infections

Adsorption of viruses to charge-modified silica

This occurs through the impairment of thioredoxin 2 (Trx2) activity, which subsequently triggers the release of a cascade of proapoptotic factors, including the notable cyclophilin D, thereby influencing the apoptotic pathways and cellular homeostasis
