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Interestingly, administration of GRN-529, a negative allosteric modulator of the mGlu5 receptor in BTBR mice, effectively rescued an ASD-like phenotype [56]
doi: 10.1152/ajpregu.00208.2003
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Discussion The increasing incidence of chronic inflammatory disorders such as IBD, T1D, and MS in the industrialized countries is a concerning development, and treatment options are still limited
