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First, the tumor-associated microbiome exhibits significant heterogeneity, including inter-tumor (e.g., differences in microbial composition between melanoma and CRC), intra-tumor (e.g., spatial distribution between tumor core and periphery), and inter-individual (influenced by host genetic background, dietary habits, and environmental factors) diversity, which complicates mechanism elucidation and precision intervention (Wang et al., 2022, Yu et al., 2022, Simpson et al., 2022)

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J Neuroimaging 30(1):517 Taylor RW et al (2004) Mitochondrial diseases: diagnosis and management

Differences Between Functional Medicine and Integrative Medicine Functional medicine asks, Why is this happening? Integrative Medicine asks, How do we get everything working together again? Both aim for long-term performance and take different paths to get there