does ethanol deplete glutathione and Alcohol: Read This Before You Have One More Oxidative pathways of alcohol metabolism.
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10.1002/jcb.28887 [DOI] [PubMed] [Google Scholar] Ghanei H, Abeyrathne PD, Lam JS, 2007

Additionally, mitochondrial dysfunction can activate the integrated stress response (ISR) [257], promoting the expression of activating transcription factor 5 (ATF5) and C/EBP homologous protein (CHOP), which further modulate cellular metabolism and apoptosis resistance [258]

J Clin Microbiol 49 , 31393142

Similar results were obtained for a medical study in which Cornus mas extracts seemed to improve the lipid profile and reduce vascular inflammation [73]
