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Dose selection in the research literature varies with the application: musculoskeletal-injury studies commonly report 200250 g twice daily near the affected site, while gastrointestinal-focused protocols use 250500 g once or twice daily, subcutaneously

This timing takes advantage of the bodys natural post-overnight fast state when insulin levels are low and fatty acid mobilization is already elevated

In studies, Refyne lasts about 12 months

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