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Other side effects like headache, heart beating, dyspnoe, edema, confusion, micturition dysfunction, loss of appetite and anxiety are even more rare and below 2% (Reichmann et al., 2002)

Pharmacol Res 176:106061

In addition, infants born to vitamin B-12supplemented mothers had higher plasma vitamin B-12 concentrations and lower tHcy and MMA concentrations, indicative of improved vitamin B-12 status

Several metabolic intermediates, such as long-chain acylcarnitines can cause oxidative stress at high levels and high levels of ROS can then cause damage to cells and tissues, leading to a further decline in performance
