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Topologically associated domains (TADs)
"If your vitamin B12 deficiency is caused by a lack of the vitamin in your diet, you may be prescribed vitamin B12 tablets to take every day between meals," explains the NHS
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As a result, the k cat / K m of K240A toward both tyrosine and DOPA was also decreased, indicating that mutation of lysine-240 to alanine might affect the affinity of enzyme and substrates by altering the conformation of adjacent amino acids, particularly H241
